Fluorphine
Product Specifications
CAS Number
6440-42-2
Target
Opioid Receptor
Related Pathways
GPCR/G Protein|||Endocrinology/Hormones|||Neuroscience
Bioactivity
Fluorphine, an analog of Brorphine, binds to the ?-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTP?S binding activity with an EC50 of 75 nM and ?-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.
Smiles
O=C1NC=2C=CC=CC2N1C3CCN(CC3)C(C4=CC=C(F)C=C4)C
Molecular Formula
C20H22FN3O
Molecular Weight
339.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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