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Se2h

Product Specifications

Target

Parasite

Related Pathways

Microbiology/Virology

Bioactivity

Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55) . Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.

Molecular Formula

C12H13ClN4O2Se

Molecular Weight

359.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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