Se2h
Product Specifications
Target
Parasite
Related Pathways
Microbiology/Virology
Bioactivity
Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55) . Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.
Molecular Formula
C12H13ClN4O2Se
Molecular Weight
359.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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