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Lucidenic acid O

Product Specifications

CAS Number

250643-33-5

Target

DNA/RNA Synthesis, HIV Protease, Reverse Transcriptase

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Proteases/Proteasome, Microbiology/Virology

Bioactivity

Lucidenic acid O is a terpene compound that acts as an inhibitor of DNA polymerases. Lucidenic lactone inhibits calf DNA polymerase-α, rat DNA polymerase-β, and HIV-1 reverse transcriptase, with IC50 values of 42 μM, 99 μM, and 69 μM, respectively.

Smiles

C[C@]12C3=C([C@]4(C)[C@@](C[C@@H]3O)([C@@](CO)(C)[C@@H](O)CC4)[H])C(=O)C[C@]1(C)[C@@H](C(CCC(O)=O)=C)C[C@@H]2O

Molecular Formula

C27H40O7

Molecular Weight

476.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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