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PDE1-IN-8

Product Specifications

Target

Others, PDE

Related Pathways

Metabolism, Others

Bioactivity

PDE1-IN-8 (Compound 3f) acts as an inhibitor of PDE1, with an IC50 of 11 nM. It hinders cAMP and cGMP signaling pathways, impeding the differentiation and proliferation of cells into myofibroblasts, and demonstrates antifibrotic effects in the Bleomycin-induced rat model of pulmonary fibrosis.

Molecular Formula

C17H11Cl2N3OS2

Molecular Weight

408.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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