FerroLOXIN-1
Product Specifications
CAS Number
2773428-48-9
Target
Ferroptosis, Lipoxygenase
Related Pathways
Metabolism, Apoptosis
Bioactivity
FerroLOXIN-1 is a potent inhibitor of 15LOX-2, selectively blocking the production of ferroptosis-promoting HOO-ETE-PE and preventing RSL3-induced ferroptosis (ferroptosis) . It interacts closely and specifically with 15LOX-2, particularly engaging with Y154, N155, and W158.
Smiles
FC1=CC=CC(=C1)N2C=C(N=C2NCC3=CC=C(C(F)=C3)C(F)(F)F)C=4C=CC=CC4
Molecular Formula
C23H16F5N3
Molecular Weight
429.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E3222-75P 200 µL
ENOA, NT (Alpha-enolase, 2-phospho-D-glycerate Hydro-lyase, Non-neural Enolase, NNE, Enolase 1, Phosphopyruvate Hydratase, C-myc Promoter-binding Protein, MBP-1, MPB-1, Plasminogen-binding Protein, MPB1, MBPB1, ENO1L1, ENO1)
Sign In for Pricing
View Details 
MBS1461360-01 0.5 mg (E-Coli)
Recombinant Caenorhabditis briggsae Serine/threonine-protein phosphatase Pgam5, mitochondrial (pgam-5), partial
Sign In for Pricing
View Details MBS1461360-02 0.05 mg (Baculovirus)
Recombinant Caenorhabditis briggsae Serine/threonine-protein phosphatase Pgam5, mitochondrial (pgam-5), partial
Sign In for Pricing
View Details MBS1461360-03 0.5 mg (Yeast)
Recombinant Caenorhabditis briggsae Serine/threonine-protein phosphatase Pgam5, mitochondrial (pgam-5), partial
Sign In for Pricing
View Details MBS1461360-04 0.05 mg (Mammalian-Cell)
Recombinant Caenorhabditis briggsae Serine/threonine-protein phosphatase Pgam5, mitochondrial (pgam-5), partial
Sign In for Pricing
View Details MBS1461360-05 1 mg (E-Coli)
Recombinant Caenorhabditis briggsae Serine/threonine-protein phosphatase Pgam5, mitochondrial (pgam-5), partial
Sign In for Pricing
View Details