FerroLOXIN-1
Product Specifications
CAS Number
2773428-48-9
Target
Ferroptosis, Lipoxygenase
Related Pathways
Metabolism, Apoptosis
Bioactivity
FerroLOXIN-1 is a potent inhibitor of 15LOX-2, selectively blocking the production of ferroptosis-promoting HOO-ETE-PE and preventing RSL3-induced ferroptosis (ferroptosis) . It interacts closely and specifically with 15LOX-2, particularly engaging with Y154, N155, and W158.
Smiles
FC1=CC=CC(=C1)N2C=C(N=C2NCC3=CC=C(C(F)=C3)C(F)(F)F)C=4C=CC=CC4
Molecular Formula
C23H16F5N3
Molecular Weight
429.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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