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NEK7-IN-1

Product Specifications

CAS Number

2738569-12-3

Target

MAPK, Others

Related Pathways

Others, MAPK

Bioactivity

NEK7-IN-1 (Compound I-15) is an inhibitor of NIMA-related kinase 7 (NEK7) with an IC50 of less than 100 nM. It also effectively inhibits the release of IL-1β, exhibiting an IC50 of less than 50 nM.

Smiles

O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)NC=3C=CC(=CC3F)C4=CN(C=5N=CN=C(N)C45)CC(O)(C)C

Molecular Formula

C30H34F4N8O2

Molecular Weight

614.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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