NEK7-IN-1
Product Specifications
CAS Number
2738569-12-3
Target
MAPK|||Others
Related Pathways
Others|||MAPK
Bioactivity
NEK7-IN-1 (Compound I-15) is an inhibitor of NIMA-related kinase 7 (NEK7) with an IC50 of less than 100 nM. It also effectively inhibits the release of IL-1?, exhibiting an IC50 of less than 50 nM.
Smiles
O=C(NC1=CC=C(C(=C1)C(F)(F)F)CN2CCN(C)CC2)NC=3C=CC(=CC3F)C4=CN(C=5N=CN=C(N)C45)CC(O)(C)C
Molecular Formula
C30H34F4N8O2
Molecular Weight
614.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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