WRN inhibitor 18

3064599-42-1

DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint

WRN inhibitor 18 (compound 306) is an orally active inhibitor of WRN with demonstrated anticancer activity in vivo.

C(O)(=O)[C@@H]1[C@H](C[C@H](C[C@H]1C(NC2=C(F)C=C(C(F)(F)F)C=C2)=O)N3CCC(F)(F)C3)C4=CC=C(N(S(=O)(=O)C=5C=C6C(=CC5)N(C)C(C)=N6)C)C=C4

C35H35F6N5O5S

751.74

Ice Packs

-20°C