FRF-06-057

Product Specifications

Target

EGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Bioactivity

FRF-06-057 is an allosteric ATP EGFR inhibitor targeting both wild-type and mutant EGFR, with IC50 values of 17 nM (LR/TM), 29 nM (LR/TM/CS), 220 nM (LR), and >1000 nM (WT) .

Molecular Formula

C19H13N3O3S

Molecular Weight

363.39

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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