GSK163929
Product Specifications
CAS Number
716354-04-0
Target
HIV Protease, CCR
Related Pathways
Microbiology/Virology, GPCR/G Protein, Immunology/Inflammation, Proteases/Proteasome
Bioactivity
GSK163929 (compound 122) is an orally active CCR5 antagonist with anti-HIV properties and demonstrates low inhibitory potency against hEGR. Administered at a dosage of 2000 mg/kg/day (i.v., 7 d), it shows no adverse effects in rats, and at 250 mg/kg/day (i.v., 7 d), it is similarly non-toxic in dogs.
Smiles
C(CN1[C@@]2(C[C@H](C[C@]1(CC2)[H])N3C=4C(N=C3C)=CC=CC4)[H])C5(CCN(C(=O)C6=CC(S(NC)(=O)=O)=C(F)C=C6Cl)CC5)C7=CC(F)=CC=C7
Molecular Formula
C36H40ClF2N5O3S
Molecular Weight
696.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV779012 1.0 µg DNA
RPL26P29 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)
Sign In for Pricing
View Details MBS6147015-01 0.1 mL
ELF4 (ETS-related Transcription Factor Elf-4, E74-like Factor 4, Myeloid Elf-1-like Factor, MEF, ELFR) (FITC)
Sign In for Pricing
View Details MBS6147015-02 5x 0.1 mL
ELF4 (ETS-related Transcription Factor Elf-4, E74-like Factor 4, Myeloid Elf-1-like Factor, MEF, ELFR) (FITC)
Sign In for Pricing
View Details 128047-ML490 100 µL
HOXD3 (Homeobox Protein Hox-D3, Homeobox Protein Hox-4A, HOX1D, HOX4A, MGC10470) (MaxLight 490)
Sign In for Pricing
View Details