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KOR agonist 3

Product Specifications

Target

Opioid Receptor

Related Pathways

Neuroscience, Endocrinology/Hormones, GPCR/G Protein

Bioactivity

KOR agonist 3 (Compound 5) is an agonist of the κ opioid receptor (κOR) with an EC50 of 0.88 nM. It also exhibits some activation of μOR, with an EC50 of 720 nM. However, KOR agonist 3 does not activate δOR at concentrations below 1 μM. Its ability to recruit β-Arrestin-2 is lower than that of U50488.

Molecular Formula

C24H24N2O3

Molecular Weight

388.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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