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GAPDH-IN-1

Product Specifications

CAS Number

252212-58-1

Target

Endogenous Metabolite

Related Pathways

Metabolism

Bioactivity

GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor, with an IC50 value of 39.31 μM for GAPDH enzyme activity. It forms a covalent adduct with the aspartic acid in the active site, displacing the enzyme's cofactor NAD+, and simultaneously enhances the reactivity of cysteine-reactive probes with the catalytic cysteine.

Smiles

N=1N=C(OC1C=2C=CC=C(OCC3OC3)C2)C=4C=CC=C(OCC5OC5)C4

Molecular Formula

C20H18N2O5

Molecular Weight

366.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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