COX-2/15-LOX-IN-6
Product Specifications
Target
Lipoxygenase, COX
Related Pathways
Immunology/Inflammation, Metabolism, Neuroscience
Bioactivity
COX-2/15-LOX-IN-6 (Compound 5l) is a dual inhibitor of COX-2 and 15-LOX with IC50 values of 0.201 μM and 11.723 μM, respectively. In serum, it suppresses the expression of PGE, TNF-α, IL-6, and iNOS, and demonstrates anti-inflammatory activity in a carrageenan-induced rat edema model.
Molecular Formula
C31H28N4O4S
Molecular Weight
552.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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