P53 Activator 13

P53 Activator 13 is an inhibitor of the 6mA methyltransferase CamA and acts as a p53 activator. It intercalates into the minor groove of DNA bound by CamA, inducing conformational changes that displace the catalytic domain from DNA and trigger DNA damage responses via p53 activation. p53 Activator 13 is applicable in cancer research.