P53 Activator 13
Product Specifications
Target
MDM-2/p53, DNA Methyltransferase
Related Pathways
Chromatin/Epigenetic, Apoptosis
Bioactivity
P53 Activator 13 is an inhibitor of the 6mA methyltransferase CamA and acts as a p53 activator. It intercalates into the minor groove of DNA bound by CamA, inducing conformational changes that displace the catalytic domain from DNA and trigger DNA damage responses via p53 activation. p53 Activator 13 is applicable in cancer research.
Molecular Formula
C33H35N9O
Molecular Weight
573.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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