HIV-1 inhibitor-79
Product Specifications
Target
Reverse Transcriptase, HIV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
HIV-1inhibitor-79 (Compound 3k) is an HIV inhibitor that demonstrates significant inhibitory activity against HIV-1 and its common mutants, with IC50 values of 1.9 nM for HIV-1, K103, 8.7 nM for L100I, and 11 nM for E138K. It exhibits low cytotoxicity and a high selectivity index (CC50 = 21.95 μM, SI = 11478) . Additionally, HIV-1inhibitor-79 shows antiviral activity against HIV-2, with an EC50 value of 6.14 μM, and effectively inhibits HIV-1 reverse transcriptase with an IC50 of 25 nM.
Molecular Formula
C21H17N7O
Molecular Weight
383.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HA723810 100 µL
Mouse/Rat PDGF-BB Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details 
55800 10 Preparations
Plasma/Serum Cell-Free Circulating DNA Purification Maxi Kit
Sign In for Pricing
View Details 
