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WRN inhibitor 17

Product Specifications

CAS Number

3064599-40-9

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Bioactivity

WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.

Smiles

C(O)(=O)[C@@H]1[C@H](C[C@@H](COC)C[C@H]1C(NC2=C(F)C=C(C(F)(F)F)C=C2)=O)C3=CC=C(N(S(=O)(=O)C=4C=C5C(=CC4)N(C)C(C)=N5)C)C=C3

Molecular Formula

C33H34F4N4O6S

Molecular Weight

690.71

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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