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LTD4 antagonist 2

Product Specifications

CAS Number

107813-86-5

Target

Leukotriene Receptor

Related Pathways

GPCR/G Protein

Bioactivity

LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R) . Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.

Smiles

O=C(O)C=1C=CC=C(OCC2=NC=3C=CC=CC3C=C2)C1

Molecular Formula

C17H13NO3

Molecular Weight

279.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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