LTD4 antagonist 2
Product Specifications
CAS Number
107813-86-5
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Bioactivity
LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 ?M for the cysteinyl leukotriene 1 receptor (CysLT1R) . Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.
Smiles
O=C(O)C=1C=CC=C(OCC2=NC=3C=CC=CC3C=C2)C1
Molecular Formula
C17H13NO3
Molecular Weight
279.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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