TS-002455

2702331-04-0

DNA/RNA Synthesis|||DNA Methyltransferase

Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

TS-002455 (Example 668) acts as an inhibitor of Lin28a-dep Z11, demonstrating an IC50 of less than 1 ?M. It is the enantiomer of TS-002266.

O=C1C=2C(N(C=C1C(O)=O)C=3C=CC(=NC3)N4CC(N(C)C)C4)=CC(=C(Cl)C2)N5[C@H](COC6=C(Cl)C(OC)=CC=N6)CCC5

C31H32Cl2N6O5

639.53

Cool pack

-20°C