EHNA
Product Specifications
CAS Number
51350-19-7
Target
Influenza Virus, Adenosine Deaminase, PDE
Related Pathways
Microbiology/Virology, Metabolism
Bioactivity
EHNA is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2) (IC50 = 4 μM) and adenosine deaminase (ADA) . It exhibits concentration-dependent inhibition of cGMP-stimulated PDE2 activity, with IC50 values of 0.8 μM in humans and 2 μM in porcine myocardium, but shows limited inhibition on unstimulated PDE2. EHNA is involved in modulating various pharmacological responses, such as antiviral, antitumor, and antiarrhythmic effects.
Smiles
[C@H](CCCCCC)([C@@H](C)O)N1C=2C(N=C1)=C(N)N=CN2
Molecular Formula
C14H23N5O
Molecular Weight
277.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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