UKH-1114
Product Specifications
CAS Number
2113664-14-3
Target
Sigma receptor
Related Pathways
GPCR/G Protein
Bioactivity
UKH-1114 is a potent σ2 receptor/Tmem97 agonist with a Ki value of 46 nM, demonstrating antinociceptive effects against mechanical hypersensitivity. This compound alleviates mechanical hypersensitivity in mice caused by nerve injury without inducing motor impairment and is a promising candidate for neuropathic pain research.
Smiles
FC(F)(F)C1=CC=C(C=C1)C=2C=CC3=C(C2)C4N(CCCO)CCCC3C4
Molecular Formula
C22H24F3NO
Molecular Weight
375.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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