PARL-IN-2
Product Specifications
Target
Mitophagy, PTEN
Related Pathways
Autophagy, PI3K/Akt/mTOR signaling
Bioactivity
PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial inner membrane protease PARL, with an EC50 value of 0.16 μM. It strongly activates the PINK1/Parkin pathway and enhances PINK1/Parkin-dependent mitophagy.
Molecular Formula
C22H23NO4
Molecular Weight
365.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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