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PARL-IN-2

Product Specifications

Target

Mitophagy, PTEN

Related Pathways

Autophagy, PI3K/Akt/mTOR signaling

Bioactivity

PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial inner membrane protease PARL, with an EC50 value of 0.16 μM. It strongly activates the PINK1/Parkin pathway and enhances PINK1/Parkin-dependent mitophagy.

Molecular Formula

C22H23NO4

Molecular Weight

365.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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