Cyano-myracrylamide
Product Specifications
CAS Number
2801702-34-9
Target
Acyltransferase
Related Pathways
Metabolism
Bioactivity
Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with an IC50 value of 1.35 μM. It also inhibits the S-palmitoylation of EGFR and CD36. In HEK293T cells expressing recombinant E. coli GobX, recombinant human MyD88, or endogenous Ras, Cyano-myracrylamide inhibits the S-palmitoylation of E. coli E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6.
Smiles
N#CCN(C(=O)C=C)CCCCCCCCCCCCCC
Molecular Formula
C19H34N2O
Molecular Weight
306.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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