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Ro 25-1553

Product Specifications

CAS Number

159427-08-4

Target

PACAP, Others

Related Pathways

Others, GPCR/G Protein

Bioactivity

Ro 25-1553 is a 31-amino acid analog of vasoactive intestinal peptide (VIP) that functions as an agonist for the VIP2 receptor (VPAC2 receptor) . In guinea pig models, Ro 25-1553 exhibits bronchodilator effects on tracheal smooth muscle contraction induced by neural stimuli or Carbachol.

Smiles

C([C@@H]1NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CN=CN4)NC(C)=O)=O)CO)=O)CC(O)=O)=O)C)=O)C(C)C)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)CCCCN)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCCN)=O)CCC(N)=O)=O)CCCC)=O)C)=O)C)=O)CCCCN)=O)CCCCNC(=O)C[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@@H]([C@@H](C)O)C(N)=O)=O)=O)=O)CCCCN)=O)CCCCN)=O)CC(C)C)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC1=O)C5=CC=C(O)C=C5

Molecular Formula

C160H258N46O46

Molecular Weight

3562.04

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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