ZG-2033
Product Specifications
CAS Number
2685739-28-8
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic, Metabolism
Bioactivity
ZG-2033 (Compound 26) is an orally active HIF-2α agonist that exhibits nanomolar activity (EC50 = 490 nM) in a luciferase reporter assay. It demonstrates an anti-anemic effect and shows synergistic effects with AKB-6548 in anemia, making it useful for the study of renal anemia.
Smiles
N=1SC=2C=CC=CC2C1NC=3C=C(OC)C=C(OC)C3
Molecular Formula
C15H14N2O2S
Molecular Weight
286.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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