What is the catalog number for PDE1-IN-9?

The catalog number for PDE1-IN-9 is T203227.

What sizes are available for PDE1-IN-9?

PDE1-IN-9 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does PDE1-IN-9 come in?

PDE1-IN-9 is available in 2 different pack sizes.

Is PDE1-IN-9 in stock?

PDE1-IN-9 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PDE1-IN-9?

PDE1-IN-9 is manufactured by Molfinity.

What is the estimated delivery time for PDE1-IN-9?

Estimated delivery time for PDE1-IN-9 is approximately 10 business day(s), depending on your location.

PDE1-IN-9

Product Specifications

CAS Number

2982945-41-3

Target

NO Synthase, PDE

Related Pathways

Immunology/Inflammation, Metabolism

Bioactivity

PDE1-IN-9 (Compound 7a) is a selective inhibitor of phosphodiesterase 1 (PDE1), targeting PDE1C with an IC50 value of 11 nM. It effectively reduces the mRNA expression of IL-1β, IL-6, TNF-α, and iNOS, while also inhibiting the production of nitric oxide (NO) and reactive oxygen species (ROS) . Additionally, PDE1-IN-9 demonstrates good metabolic stability in rat liver microsomes.