FXR agonist 11
Product Specifications
CAS Number
2768502-17-4
Target
FXR
Related Pathways
Metabolism
Bioactivity
FXR agonist11 (Compound 14) is an FXR activator with an EC50 of 1.2 ?M and a maximal effect of 73.7%. It significantly increases GSH levels in the liver and is used to study drug-induced liver injury.
Smiles
O=C(O)C=1C=CC=C(C1)NC(=O)COC2=CC=C3C(=C2)NC(=O)CC3
Molecular Formula
C18H16N2O5
Molecular Weight
340.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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