QKY-613
Product Specifications
CAS Number
2484713-92-8
Target
Others|||cGAS
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
QKY-613 is a prodrug designed to enhance immune surveillance by targeting nucleic acid modification pathways. It selectively facilitates the incorporation of 6mdA (N6-methyl-deoxyadenosine) into viral DNA, boosting the DNA's phase separation potential and subsequently increasing cGAS activation levels to strengthen host immune surveillance. In mouse models of viral infection, QKY-613 significantly reduced mortality in aged mice. This compound holds promise for studying immune surveillance mechanisms based on nucleic acid modifications.
Smiles
N(C)C1=C2C(N(C=N2)C3O[C@H](COP(OC4=CC=CC=C4)(N[C@H](C(OCC5=CC=CC=C5)=O)C)=O)[C@@H](O)C3)=NC=N1
Molecular Formula
C27H31N6O7P
Molecular Weight
582.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/296282095246901285/T203193
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RC205373L2V 200 µL
cIAP1 (BIRC2) (NM_001166) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details SIPC701Hu01-01 10 µg
Recombinant Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
Ask
View Details SIPC701Hu01-02 50 µg
Recombinant Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
Ask
View Details 
SIPC701Hu01-03 200 µg
Recombinant Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
Ask
View Details SIPC701Hu01-04 1 mg
Recombinant Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
Ask
View Details 
SIPC701Hu01-05 5 mg
Recombinant Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3)
Ask
View Details