Adhibin
Product Specifications
Target
Myosin
Related Pathways
Cytoskeletal Signaling
Bioactivity
Adhibin is an allosteric inhibitor of RhoGAP class IX myosin (RhoGAP class IXmyosin), effectively inhibiting Myo9 ATPase in both mammals and invertebrates with an IC50 of 2.5 μM and 2.6 μM, respectively. It binds to ATPase, disrupting myosin's motor functions, blocking RhoGTPase-related signaling pathways, and affecting cellular migration, adhesion, and division. Adhibin is applicable for research in cancer metastasis.
Molecular Formula
C13H9Br2NO
Molecular Weight
355.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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