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P-gp inhibitor 27

Product Specifications

Target

P-gp, Others

Related Pathways

Membrane transporter/Ion channel, Neuroscience, Others

Bioactivity

P-gp inhibitor 27 (Compound D2) is an inhibitor of P-glycoprotein (P-gp) that reduces the expression of P-gp and MRP1. It increases the accumulation of Rh123 in A2780/T cells and reverses multidrug resistance to Paclitaxel (EC50 of 88 nM) and Cisplatin.

Molecular Formula

C25H25N3O4

Molecular Weight

431.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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