P-gp inhibitor 27
Product Specifications
Target
P-gp|||Others
Related Pathways
Membrane transporter/Ion channel|||Neuroscience|||Others
Bioactivity
P-gp inhibitor 27 (Compound D2) is an inhibitor of P-glycoprotein (P-gp) that reduces the expression of P-gp and MRP1. It increases the accumulation of Rh123 in A2780/T cells and reverses multidrug resistance to Paclitaxel (EC50 of 88 nM) and Cisplatin.
Molecular Formula
C25H25N3O4
Molecular Weight
431.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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