What is the catalog number for (E/Z) -Droloxifene?

The catalog number for (E/Z) -Droloxifene is T203143.

What sizes are available for (E/Z) -Droloxifene?

(E/Z) -Droloxifene is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does (E/Z) -Droloxifene come in?

(E/Z) -Droloxifene is available in 2 different pack sizes.

Is (E/Z) -Droloxifene in stock?

(E/Z) -Droloxifene is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures (E/Z) -Droloxifene?

(E/Z) -Droloxifene is manufactured by Molfinity.

What is the estimated delivery time for (E/Z) -Droloxifene?

Estimated delivery time for (E/Z) -Droloxifene is approximately 10 business day(s), depending on your location.

(E/Z) -Droloxifene

Product Specifications

CAS Number

165813-01-4

Target

Apoptosis, Estrogen Receptor/ERR

Related Pathways

Apoptosis, Endocrinology/Hormones

Bioactivity

(E/Z) -Droloxifene is a mixture comprising (E) -Droloxifene, known as a selective estrogen receptor modulator, and (Z) -Droloxifene. (E) -Droloxifene binds to estrogen receptors (ER) in rabbit uterine homogenate with an IC50 of 24 nM. It increases uterine weight in immature rats and reduces the uterine weight increase caused by estradiol in juvenile rats. Additionally, (E) -Droloxifene inhibits the growth of human breast cancer cells MCF-7, ZR-75-1, and T47D stimulated by 17β-estradiol. In contrast, (Z) -Droloxifene shows weak binding to ER and exhibits neither estrogenic nor anti-estrogenic activity.