Ap4dT
Product Specifications
CAS Number
1146545-74-5
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Bioactivity
Ap4dT serves as an inhibitor of human adenylate kinase isozyme 1 (hAK1), effectively suppressing the synthesis of ATP and ADP, with IC50 values of 42 ?M and 38 ?M, respectively.
Smiles
O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP(OP(OC[C@H]2O[C@@H](N3C(NC(C(C)=C3)=O)=O)C[C@@H]2O)([O-])=O)([O-])=O)([O-])=O)([O-])=O)N4C5=NC=NC(N)=C5N=C4.[NH4+].[NH4+].[NH4+].[NH4+]
Molecular Formula
C20H41N11O20P4
Molecular Weight
879.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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