NLRP3-IN-61
Product Specifications
CAS Number
3060585-94-3
Target
NOD-like Receptor (NLR), Pyroptosis
Related Pathways
Immunology/Inflammation, Apoptosis
Bioactivity
NLRP3-IN-61 (Compound 1) is an inhibitor of NLRP3. It suppresses pyroptosis in THP-1 cells with an IC50 of 12.6 nM and inhibits IL-β release with an IC50 of 25.3 nM.
Smiles
OC=1C(C=2N=C3C(OC(=N3)[C@@H]4CCC(=O)NC4)=CC2)=C(C)C=C5C1CCC5
Molecular Formula
C21H21N3O3
Molecular Weight
363.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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