Actinobolin hemisulfate

Product Specifications

CAS Number

18802-17-0

Target

Antibacterial|||Antibiotic

Related Pathways

Microbiology/Virology

Bioactivity

Actinobolin hemisulfate ((+) -Actinobolin hemisulfate) is the hemisulfate salt form of Actinobolin. This antibiotic functions by targeting ribosomes in both bacteria and eukaryotes to inhibit protein synthesis. Actinobolin hemisulfate exhibits inhibitory effects on Mycobacterium smegmatis, Escherichia coli, and rabbit reticulocyte lysate (RRL) with IC50 values of 19.2, 27.9, and 288 ?mol/L, respectively.

Smiles

O=S(O)(O)=O.C[C@H](N)C(N[C@@H]1[C@@]2([H])C(C(O[C@@H]1C)=O)=C(C[C@H]([C@@H]2O)O)O)=O.C[C@H](N)C(N[C@@H]3[C@@]4([H])C(C(O[C@@H]3C)=O)=C(C[C@H]([C@@H]4O)O)O)=O