LDHA-IN-9
Product Specifications
CAS Number
862719-04-8
Target
Apoptosis, Dehydrogenase
Related Pathways
Metabolism, Apoptosis
Bioactivity
LDHA-IN-9 (Compound 1g) is an LDH-A inhibitor with an IC50 of 25 nM. It inhibits the proliferation of DLD-1 cells by inducing apoptosis, with a GI50 of 27 μM. In mouse models, LDHA-IN-9 exhibits antitumor activity without significant toxicity at a dose of 25 mg/kg.
Smiles
O=C(OC)C1=C(C=2C(Br)=CC=CC2N1O)COCCCCCC
Molecular Formula
C17H22BrNO4
Molecular Weight
384.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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