What is the catalog number for IRF1-IN-2?

The catalog number for IRF1-IN-2 is T203076.

What sizes are available for IRF1-IN-2?

IRF1-IN-2 is available in the following size(s): 1 mL - 10 mM (in DMSO), 25 mg, 50 mg, 100 mg.

How many pack sizes does IRF1-IN-2 come in?

IRF1-IN-2 is available in 4 different pack sizes.

Is IRF1-IN-2 in stock?

IRF1-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IRF1-IN-2?

IRF1-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for IRF1-IN-2?

Estimated delivery time for IRF1-IN-2 is approximately 10 business day(s), depending on your location.

IRF1-IN-2

Product Specifications

CAS Number

708245-32-3

Target

Pyroptosis, Caspase, PARP, Interleukin, Glutathione Peroxidase, IFNAR

Related Pathways

Chromatin/Epigenetic, Metabolism, Apoptosis, DNA Damage/DNA Repair, Proteases/Proteasome, Immunology/Inflammation

Purity

0.9985

Bioactivity

IRF1-IN-2 is a small molecule inhibitor of interferon regulatory factor 1 (IRF1) that functions by reducing the binding affinity of IRF1 for the caspase-1 (CASP1) gene promoter. this inhibition subsequently suppresses critical cell death signaling pathways, such as pyroptosis, and provides robust protection against ionizing radiation-induced skin inflammatory damage in preclinical models.