DDC-01-163
Product Specifications
CAS Number
2140806-84-2
Target
PROTACs, EGFR
Related Pathways
Angiogenesis, JAK/STAT signaling, PROTAC, Tyrosine Kinase/Adaptors
Bioactivity
DDC-01-163 is a selective PROTAC degrader targeting EGFR mutants, with an IC50 of 45 nM.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCOCCN4CCN(C=5N=CC(=CC5)C6=CC=C7C(=C6)C(=O)N(C7)C(C(=O)NC8=NC=CS8)C=9C=CC=CC9)CC4)C3C2=O)CC1
Molecular Formula
C49H51N9O9S
Molecular Weight
942.05
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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