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FLT3-ITD-IN-2

Product Specifications

Target

FLT

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.

Molecular Formula

C39H50N8O6

Molecular Weight

726.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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