FLT3-ITD-IN-2
Product Specifications
Target
FLT
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.
Molecular Formula
C39H50N8O6
Molecular Weight
726.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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TA805187BM 100 µL
Thyroid Hormone Receptor alpha (THRA) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI2A2]
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