ACT-451840
Product Specifications
CAS Number
1984890-99-4
Target
Parasite
Related Pathways
Microbiology/Virology
Purity
0.9607
Bioactivity
ACT-451840 is capable of eliminating both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral activity, potency, low toxicity, rapid onset of action in all asexual blood stages of Plasmodium, and a mechanism of action similar to that of artemisinin derivatives. In in vivo experiments, ACT-451840 showed excellent antimalarial effects at a dose of 30 mg/kg, with a parasite reduction rate of 99.80%.
Smiles
CC(=O)N1CCN(CC1)c1ccc(CN([C@@H](Cc2ccccc2)C(=O)N2CCN(Cc3ccc(cc3)C#N)CC2)C(=O)\C=C\c2ccc(cc2)C(C)(C)C)cc1
Molecular Formula
C47H54N6O3
Molecular Weight
750.97
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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