EAPB-0503
Product Specifications
CAS Number
1140627-77-5
Target
Apoptosis, PARP, Bcr-Abl
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Apoptosis, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair
Bioactivity
EAPB-0503, an imidazoquinoxaline derivative and an analog of Imiquimod, selectively reduces HDM2 expression and activates the p53 pathway in cells expressing NPM1c, thereby inducing apoptosis.
Smiles
N=1C=C(C2=CC=CC(OC)=C2)N3C1C(=NC=4C=CC=CC43)NC
Molecular Formula
C18H16N4O
Molecular Weight
304.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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