EAPB-0503

Product Specifications

CAS Number

1140627-77-5

Target

Apoptosis|||PARP|||Bcr-Abl

Related Pathways

Chromatin/Epigenetic|||Angiogenesis|||Apoptosis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair

Bioactivity

EAPB-0503, an imidazoquinoxaline derivative and an analog of Imiquimod, selectively reduces HDM2 expression and activates the p53 pathway in cells expressing NPM1c, thereby inducing apoptosis.

Smiles

N=1C=C(C2=CC=CC(OC)=C2)N3C1C(=NC=4C=CC=CC43)NC

Molecular Formula

C18H16N4O

Molecular Weight

304.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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