Zotiraciclib citrate
Product Specifications
CAS Number
1204918-73-9
Bioactivity
Zotiraciclib (also known as TG02 and SB1317) is an innovative small-molecule compound with potent inhibitory effects on CDK, JAK2, and FLT3. By inhibiting cyclin-dependent kinase 9 (CDK9) and depleting Myc, it serves as a treatment for cancers that can penetrate the blood-brain barrier. Zotiraciclib is one of the numerous CDK inhibitors under investigation; other compounds targeting CDK9, utilized for treating acute myeloid leukemia, include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80% of glioblastomas exhibiting this characteristic.
Smiles
OC(=O)CC(O)(CC(O)=O)C(O)=O.CN1C\C=C\CCOC2=CC(=CC=C2)C3=CC=NC(NC4=CC=CC(C1)=C4)=N3
Molecular Formula
C29H32N4O8
Molecular Weight
564.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K4218104 1.0 µg DNA
Olfr556 sgRNA CRISPR Lentivector (Mouse) (Target 3)
Sign In for Pricing
View Details 
MBS9008898 Inquire
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) HSP26.5 Polyclonal Antibody
Sign In for Pricing
View Details