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Holanamine

Product Specifications

CAS Number

6869-29-0

Bioactivity

Holanamine is a compound used to combat Leishmania donovani and has been identified as a non-competitive inhibitor of LdToP1B. Docking studies reveal that Holanamine exerts its antileishmanial effects through hydrogen bonds and hydrophobic interactions with the N-terminal and hinge regions of the LTop1B large subunit.

Smiles

C[C@H]1[C@@]2([C@@]3([C@]([C@]4([C@]([C@H](O)C3)([C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H])(CC2)[H])C=N1)[H]

Molecular Formula

C21H27NO2

Molecular Weight

325.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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