M4K2281
Product Specifications
CAS Number
3034840-19-9
Bioactivity
M4K2281 is a potent and selective inhibitor of ALK2 with a half-maximal inhibitory concentration (IC50) of 2 nanomolar. In both biochemical and cellular assays, M4K2281 and M4K2308 demonstrate strong efficacy against ALK2. Moreover, M4K2281 exhibits a brain-to-plasma ratio that ranges from moderate to high.
Smiles
N1=CC(C2=CC(OC)=C(OC)C(OC)=C2)=C3C(=C1)C4=CC=C(C=C4OCC3)N5CCN(C)CC5
Molecular Formula
C27H31N3O4
Molecular Weight
461.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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